Priniciples and practice of pediatric oncology, 4th, pizzo pa, poplack dg eds, lippincott, williams and wilkins, philadelphia 2000. Ewing s sarcoma is genetically characterized in most cases with a cytogenetic abnormality, which is a chromosomal disorder, associated with a translocation. Ewing sarcoma primitive or peripheral neuroectodermal tumor. Ewings sarcoma bone 87% extraosseous ewings sarcoma 8% peripheral pnet5% askins tumor 2. Ewing sarcoma es and peripheral primitive neuroectodermal tumor pnet comprise the same spectrum of neoplastic diseases known as the ewing sarcoma family of tumors eft, which also includes malignant small cell tumor of the chest wall askin tumor and atypical es. Treatment of newly diagnosed ewing s sarcoma family of tumours. Ewing s sarcoma of bone and soft tissue and the peripheral primitive neuroectodermal tumors. Fast growing extraskeletal ewing sarcoma in a 2 year old patient. The ewing sarcoma family includes ewing bone sarcoma, primitive neuroectodermal tumor, extraosseous ewings sarcoma, and askim tumor. The ewing sarcoma family includes ewing bone sarcoma, primitive neuroectodermal tumor, extraosseous ewing s sarcoma, and askim tumor. Ewings sarcoma is genetically characterized in most cases with. Girish, sanjay murgod department of oral pathology and microbiology, rajarajeswari dental college and hospital, bengaluru, karnataka, india abstract ewing sarcoma is a rare sarcoma of bone and soft tissue that uncommonly involve the head and neck. Treatment of the ewing sarcoma family of tumors uptodate.